Thermo Fisher Scientific Phospho-EphA2/EphA3/EphA4 (Tyr588, Tyr596) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human EPHA2(Accession P29317), corresponding to amino acid residues around phosphorylated Tyr588. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EphA2/EphA3/EphA4,uniProtId:P29317-1,ncbiNodeId:9606,antigenRange:588,antigenLength:976,antigenImageFileName:PA5-99134_EphA2EphA3EphA4_P29317-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99134_EphA2EphA3EphA4_P29317-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:EphA2/EphA3/EphA4,uniProtId:P29320-1,ncbiNodeId:9606,antigenRange:588|596,antigenLength:983,antigenImageFileName:PA5-99134_EphA2EphA3EphA4_P29320-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99134_EphA2EphA3EphA4_P29320-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:EphA2/EphA3/EphA4,uniProtId:P54764-1,ncbiNodeId:9606,antigenRange:588|596,antigenLength:986,antigenImageFileName:PA5-99134_EphA2EphA3EphA4_P54764-1_Rabbit.svg,antigenImageFileNamePDP:PA5-99134_EphA2EphA3EphA4_P54764-1_Rabbit_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2818067

Product Specific Information

Antibody detects endogenous levels of EPHA2/3/4 only when phosphorylated at Tyrosine 588 and 596.

Target Information

The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1(Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12),EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3(Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, Ephrin-A2 (Elf-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.