Thermo Fisher Scientific TWEAK Polyclonal Antibody
TWEAK 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF 등 다양한 응용에 적합합니다. 인체 및 마우스 시료에 반응하며, 고순도의 Affinity Chromatography 정제 제품입니다. PBS/glycerol buffer에 보존되어 안정적인 장기 보관이 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TNFSF12 (Accession O43508), corresponding to amino acid residues M1–L35 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818137 |
Product Specific Information
Antibody detects endogenous levels of total TWEAK.
Target Information
TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein, although a smaller, biologically active form can also be generated by cleavage near the cell membrane.
TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, and stimulation of apoptosis. The TWEAK signal transduction pathway appears to signal via TweakR/Fn14 in a manner similar to other TNFSF members that bind receptors lacking death domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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