Thermo Fisher Scientific PPHLN1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PPHLN1. Recombinant protein control fragment (Product #RP-97735). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PPHLN1,uniProtId:Q8NEY8-1,ncbiNodeId:9606,antigenRange:36-144,antigenLength:458,antigenImageFileName:PA5-58583_PPHLN1_Q8NEY8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58583_PPHLN1_Q8NEY8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645818

Product Specific Information

Immunogen sequence: KKPPLLDRPG EGSYNRYYSH VDYRDYDEGR SFSHDRRSGP PHRGDESGYR WTRDDHSASR QPEYRDMRDG FRRKSFYSSH YARERSPYKR DNTFFRESPV GRKDSPHSR

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.

Target Information

The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.