Thermo Fisher Scientific TNFRSF14 Monoclonal Antibody (1E4)
인간 TNFRSF14 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot과 ELISA에 사용 가능. 친화 크로마토그래피로 정제된 액상 형태로 제공되며, PBS(pH 7.4) 버퍼에 보존제 없이 포함. -20°C에서 보관하며 반복 동결·해동은 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E4 |
| Immunogen | TNFRSF14 (AAH02794.1, 38 a.a. ~ 200 a.a.) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ALPSCKEDEY PVGSECCPKC SPGYRVKEAC GELTGTVCEP CPPGTYIAHL NGLSKCLQCQ MCDPAMGLRA SRNCSRTENA VCGCSPGHFC IVQDGDHCAA CRAYATSSPG QRVQKGGTES QDTLCQNCPP GTFSPNGTLE ECQHQTKCSW LVTKAGAGTS SSH
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily and functions as a cellular mediator for herpes simplex virus (HSV) entry by binding to viral envelope glycoprotein D (gD). The cytoplasmic region of TNFRSF14 interacts with TRAF family members, mediating signal transduction pathways that activate immune responses. Activation in T cells promotes proliferation and cytokine production, contributing to inflammation and enhanced CTL-mediated tumor immunity. Multiple alternatively spliced variants exist, though full-length forms of some remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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