Thermo Fisher Scientific hnRNP L Polyclonal Antibody
Human 및 Mouse 시료에서 hnRNP L 단백질을 검출하는 Rabbit Polyclonal Antibody. Western blot, IHC(P), ICC/IF 등 다양한 응용에 적합. 합성 펩타이드 면역원 기반으로 제작되었으며, 고순도 친화 크로마토그래피 정제. -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HNRNPL (Accession P14866), corresponding to amino acid residues Q69–V119 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818364 |
Product Specific Information
This antibody detects endogenous levels of total hnRNP L.
Target Information
Heterogeneous nuclear RNAs (hnRNAs), including mRNA precursors and mature mRNAs, associate with specific proteins to form heterogeneous ribonucleoprotein (hnRNP) complexes. hnRNP L is one of the proteins stably associated with these complexes and plays a major role in the formation, packaging, processing, and function of mRNA. It is predominantly localized in the nucleoplasm as part of the hnRNP complex but has also been identified outside the nucleus. hnRNP proteins shuttle between the nucleus and cytoplasm, suggesting potential cytoplasmic functions. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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