Thermo Fisher Scientific GILZ Polyclonal Antibody
GILZ(TSC22D3) 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TSC22D3 (Accession Q99576), corresponding to amino acid residues Y15–L65 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818730 |
Product Specific Information
Antibody detects endogenous levels of total TSC-22R.
Target Information
The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules.
TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such as NF-Kappa-B and AP-1. It functions as a transcriptional co-activator for various nuclear receptors and NF-Kappa-B and is involved in the differentiation of mesenchymal stem cells toward osteoblasts and bone formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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