Thermo Fisher Scientific MAPK8IP1 Monoclonal Antibody (OTI1D9), TrueMAB
MAPK8IP1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1D9). Western blot 및 IHC(P)에서 검증됨. 인간 시료 반응성. PBS/BSA/glycerol buffer에 보관, -20°C에서 안정적. 연구용으로만 사용 가능.
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- TA809895
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- pk
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D9 |
| Immunogen | Full length human recombinant protein of human MAPK8IP1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene regulates pancreatic beta-cell function and is similar to the mouse JIP-1 protein, a known regulator of c-Jun N-terminal kinase (MAPK8). It inhibits MAPK8-mediated transcription factor activation and reduces IL-1 beta and MEKK1-induced apoptosis in pancreatic beta cells. Additionally, it acts as a DNA-binding transactivator of the glucose transporter GLUT2. REST (RE1-silencing transcription factor) represses its expression in insulin-secreting beta cells. Mutations in this gene have been linked to type 2 diabetes susceptibility.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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