Thermo Fisher Scientific NREP Polyclonal Antibody
인간 NREP 단백질을 인식하는 Rabbit Polyclonal Antibody로 다양한 연구용 응용 가능. WB 및 IHC(P) 실험에 최적화된 희석 범위 제공. 고순도 affinity chromatography 정제. 안정적 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human NREP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692062 |
Target Information
P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function, and axonal regeneration. It is found in the granular layer of the cerebellum and expressed at lower levels in hippocampus, olfactory bulb, kidney, liver, and heart. When expressed ectopically, P311 augments glioma motility. In mice, P311 is enriched within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration, and promotes fibroblast differentiation into myofibroblasts. Ser-59 phosphorylation decreases P311 stability; the gene encoding P311 maps to human chromosome 5q22.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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