Thermo Fisher Scientific SEPT5 Polyclonal Antibody
SEPT5 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, 인간, 마우스, 랫트 반응성을 보입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- SEPT-501AP
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SEPT5 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 300–350 of SEPT5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The SEPT5 gene belongs to the septin family of nucleotide-binding proteins, initially described in yeast as regulators of the cell division cycle. Septins are highly conserved across species such as yeast, Drosophila, and mouse, and play key roles in cytoskeletal organization. Disruption of septin function can impair cytokinesis, leading to multinucleate or polyploid cells.
This gene is located on chromosome 22q11, a region frequently deleted in DiGeorge and velocardiofacial syndromes. Translocations involving SEPT5 and the MLL gene have been observed in acute myeloid leukemia. Two transcripts (2.2 kb and 3.5 kb) have been identified, differing in polyadenylation site usage. An alternatively spliced variant with a distinct 5′ end has also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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