Thermo Fisher Scientific ARTS Polyclonal Antibody
Western blot, ELISA, IP 등 다양한 응용에 적합한 ARTS 폴리클로날 항체. Rabbit IgG 기반으로 높은 특이성과 재현성을 제공. 합성 펩타이드 면역원으로 제작되어 인간, 마우스, 랫트 시료에 반응. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 400–450 on SEPT4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Apoptosis is related to many diseases and developmental processes. Mitochondrial proteins such as cytochrome c, Apaf-1, and AIF play important roles in apoptosis. A novel mitochondrial septin-like protein, designated ARTS (Apoptosis Related protein in TGF-beta Signaling pathway), has been identified.
ARTS, encoded by the human septin H5/PNUTL2/CDCrel2b gene, localizes to mitochondria and translocates to the nucleus during apoptosis. It is expressed in many tissues and enhances cell death induced by TGF-beta and, to a lesser extent, by TNF-α and Fas ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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