
Thermo Fisher Scientific NAE1 Monoclonal Antibody (OTI1E10), TrueMAB
Thermo Fisher Scientific의 NAE1 단클론 항체(OTI1E10)는 인간 NAE1 단백질을 인식하는 Mouse IgG1 항체로, WB 및 IHC(P)에서 검증됨. 고순도의 액상 형태로 제공되며, PBS/1% BSA/50% glycerol buffer에 보관. 세포주기 조절 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–274 of human NAE1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene binds to the beta-amyloid precursor protein, which is a cell surface protein with signal-transducing properties and is thought to play a role in the pathogenesis of Alzheimer’s disease.
In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint.
Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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