Thermo Fisher Scientific UBE2T Polyclonal Antibody, MaxPab
Rabbit polyclonal antibody against human UBE2T protein. Validated for Western blot applications. Affinity purified, liquid form without preservative. Involved in ubiquitination and DNA repair pathway studies. For research use only.
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Applications
- Western Blot (WB): Tested dilution 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | UBE2T (NP_054895.1, 1–197 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MQRASRLKRE LHMLATEPPP GITCWQDKDQ MDDLRAQILG GANTPYEKGV FKLEVIIPER YPFEPPQIRF LTPIYHPNID SAGRICLDVL KLPPKGAWRP SLNIATVLTS IQLLMSEPNP DDPLMADISS EFKYNKPAFL KNARQWTEKH ARQKQKADEE EMLDNLPEAG DSRVHNSTQK RKASQLVGIE KKFHPDV
Target Information
UBE2T is involved in the covalent conjugation of ubiquitin to proteins, regulating diverse cellular pathways. Ubiquitin is transferred to target proteins via the coordinated action of E1 (activating enzyme), E2 (conjugating enzyme such as UBE2T), and E3 (ligase).
UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates, mediates monoubiquitination, and participates in mitomycin-C (MMC)-induced DNA repair. It also catalyzes monoubiquitination of FANCD2, a key step in the DNA damage pathway.
Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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