Thermo Fisher Scientific MRPL18 Polyclonal Antibody, MaxPab

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MALRSRFWGL FSVCRNPGCR FAALSTSSEP AAKPEVDPVE NEAVAPEFTN RNPRNLELLS VARKERGWRT VFPSREFWHR LRVIRTQHHV EALVEHQNGK VVVSASTREW AIKKHLYSTR NVVACESIGR VLAQRCLEAG INFMVYQPTP WEAASDSMKR LQSAMTEGGV VLREPQRIYE

Target Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed.
Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.
Among different species, the proteins comprising the mitoribosome differ greatly in sequence and sometimes in biochemical properties, preventing easy recognition by sequence homology.
This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length causing an extra amino acid near the N-terminus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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