Thermo Fisher Scientific Ly-6E Recombinant Rabbit Monoclonal Antibody (HL1933)
Ly-6E 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ICC 등 다양한 응용에 사용 가능. HEK293 세포에서 발현된 recombinant 항체이며, Protein A로 정제됨. 사람 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공됨.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL1933 |
| Immunogen | Recombinant fragment of human LY6E |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093130 |
Target Information
Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in the bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 expression varies between the two allotypes.
Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1⁺ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1⁺ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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