Thermo Fisher Scientific CRACC Polyclonal Antibody
인간 CRACC(CD319)을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. 면역세포 활성 연구에 적합하며 ICC/IF에 사용 가능합니다. 고순도 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific CRACC Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CRACC (CD319). Recombinant protein control fragment (Product #RP-105198) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664878 |
Product Specific Information
Immunogen sequence:
SGPVKELVGSV GGAVTFPLKS KVKQVDSIVW TFNTTPLVTI QPEGGTIIVT QNRNRERVDF PDGGYSLKLS KLKKNDSGIY YVGIYSSSL
Highest antigen sequence identity to the following orthologs:
- Mouse: 49%
- Rat: 43%
Target Information
SLAMF7 contains one Ig-like C2-type domain. Isoform 1 mediates NK cell activation through a SAP-independent, ERK-mediated pathway and may play a role in lymphocyte adhesion. Isoform 3 does not mediate activation.
SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro).
SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung, and trachea. Expression detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. Isoform 3 is expressed at much lower levels than isoform 1.
There are three named isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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