Thermo Fisher Scientific U2AF1L4 Polyclonal Antibody
Thermo Fisher Scientific의 U2AF1L4 Polyclonal Antibody는 인간 U2AF1L4 단백질을 인식하는 토끼 유래 IgG 항체로, ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, RNA 결합 및 프리-mRNA 스플라이싱 연구에 활용됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human U2AF1L4. Recombinant protein control fragment (Product #RP-107085) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664215 |
Product Specific Information
Immunogen sequence:
PRGSILATIPE RGTIGVPLIT GMAASEALAP LPFTPNRDRC SWQDLSSKP
Highest antigen sequence identity to the following orthologs:
- Mouse: 33%
- Rat: 32%
Target Information
RNA-binding protein that functions as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein and protein-RNA interactions required for accurate 3′-splice site selection. Enhances the binding of U2AF2 to weak pyrimidine tracts and participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3′-splice site, with preference for AGC or AGA.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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