
Thermo Fisher Scientific FAT1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human FAT1 protein. Validated for IHC (Paraffin) at 1:50–1:200 dilution. Unconjugated, antigen affinity purified, supplied in PBS with glycerol and sodium azide. For research use only.
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- PA554910
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAT1. Recombinant protein control fragment (Product #RP-101000) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641516 |
Product Specific Information
Immunogen sequence:
NFQRALRNIL GVRRNDIQIV SLQSSEPHPH LDVLLFVEKP GSAQISTKQL LHKINSSVTD IEEIIGVRIL NVFQKLCAGL DCPWKFCDEK VSVDESVMST HSTARLSFVT PRHHRAAVCL CKEGRCP
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 90%
Target Information
The FAT1 gene is an ortholog of the Drosophila fat gene, encoding a tumor suppressor essential for controlling cell proliferation during development. The gene product belongs to the cadherin superfamily, featuring 34 tandem cadherin-type repeats, five EGF-like repeats, and one laminin A-G domain. It is highly expressed in fetal epithelia and likely functions as an adhesion molecule and/or signaling receptor, playing roles in developmental processes and cell communication. Transcript variants from alternative splicing or promoter usage exist but are not fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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