Thermo Fisher Scientific BAIAP2L1 Polyclonal Antibody
Thermo Fisher Scientific의 BAIAP2L1 폴리클로날 항체로, 인간 시료에 반응하며 WB, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 0.2 mg/mL 농도로 제공됩니다. 세포 골격 및 신호전달 연구에 활용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BAIAP2L1. Recombinant protein control fragment (Product #RP-92594). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638462 |
Product Specific Information
Immunogen sequence:
DYLECLSMGA AADRRADSAR TTSTFKAPAS KPETAAPNDA NGTAKPPFLS GENPFATVKL RPTVTNDRSA P
Highest antigen sequence identity to the following orthologs:
- Mouse: 71%
- Rat: 75%
Target Information
This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided into two groups, IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain.
The protein encoded by this gene contains a conserved IMD (F-actin bundling domain) at the N-terminus and a canonical SH3 domain near the C-terminus, classifying it as IRSp53-like.
It acts as a substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac.
This protein is involved in signal transduction pathways that link plasma membrane deformation and actin cytoskeleton remodeling.
Overexpression in mammalian cells promotes actin assembly and membrane protrusions, and it is essential for forming a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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