Thermo Fisher Scientific CYP1B1 Polyclonal Antibody
CYP1B1 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunocytochemistry에 적합하며, 인간 및 생쥐 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태로 안정적 보관 가능.
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- PA528040
- 판매단위
- pk
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Thermo Fisher Scientific CYP1B1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- Immunocytochemistry (ICC/IF): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 224–492 of Human Cytochrome P450 1B1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2545516 |
Product Specific Information
- Recommended positive controls: 293T, mouse lung
- Predicted reactivity: Mouse (84%), Rat (84%), Dog (82%), Rhesus Monkey (94%), Bovine (82%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CYP1B1 is a 543 amino acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 superfamily of enzymes, which are monooxygenases catalyzing reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17β-estradiol, and is implicated in ocular development. Mutations in CYP1B1 are associated with primary congenital glaucoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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