Thermo Fisher Scientific CTNNBL1 Polyclonal Antibody
CTNNBL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적 액상 형태. 인간, 마우스, 랫트 반응성.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CTNNBL1/Beta catenin like 1, amino acids 381–480 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CTNNBL1 protein is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. It also functions as a nuclear localization sequence binding protein and interacts with activation-induced deaminase, playing a role in antibody diversification. CTNNBL1 may be associated with obesity development. Alternative splicing results in multiple transcript variants, and a pseudogene is defined on the X chromosome. Diseases associated with CTNNBL1 include Immunodeficiency 99 with Hypogammaglobulinemia and Autoimmune Cytopenias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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