Thermo Fisher Scientific CALHM1 Polyclonal Antibody
CALHM1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Frozen)에서 검증됨. Alzheimer’s disease 연구에 활용 가능. 동결건조 형태로 제공되며 -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)EAMNHDLELGHTHG, corresponding to amino acid residues 252–265 of human calcium homeostasis modulator protein 1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735563 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by neuronal loss and senile plaques composed of aggregated amyloid-beta (Aβ) peptides derived from amyloid precursor protein (APP).
CALHM1 (Calcium Homeostasis Modulator 1) is a multipass transmembrane glycoprotein that regulates cytosolic Ca²⁺ concentration and Aβ levels. Some studies indicate an association between CALHM1 and AD risk, while others do not.
CALHM1 may modulate Ca²⁺-dependent proteolytic processing of APP by controlling cytosolic Ca²⁺ levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-77340_CALHM1_Q8IU99-1_Rabbit.svg)
(이미지: PA5-77340_CALHM1_Q8IU99-1_Rabbit_PDP.jpeg)
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