Thermo Fisher Scientific TRPML1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)GRRASETERLLTPN, corresponding to amino acid residues 6-19 of mouse TRPLM1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRPML1,uniProtId:Q99J21-1,ncbiNodeId:10090,antigenRange:6-19,antigenLength:580,antigenImageFileName:PA5-77337_TRPML1_Q99J21-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77337_TRPML1_Q99J21-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2736742

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20C upon receipt.

Reconstitute using 50 uL deionized water.

Target Information

Defects in Mucolipin-1 are the cause of mucolipidosis type IV (MLIV), also known as sialolipidosis. MLIV is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration and strabismus. Storage bodies of lipids and water-soluble substances are seen by electron microscopy in almost every cell type of the patients. Most patients are unable to speak or walk independently and reach a maximal developmental level of 1-2 years. All patients have constitutive achlorhydia associated with a secondary elevation of serum gastrin levels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.