Thermo Fisher Scientific NKIRAS1 Monoclonal Antibody (OTI1D2), TrueMAB
Human NKIRAS1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1D2). Western blot 및 Immunocytochemistry에 적합. Affinity chromatography로 정제된 액상 형태, PBS/BSA/glycerol buffer에 보존. -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D2 |
| Immunogen | Full length human recombinant protein of human NKIRAS1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KappaB ras-1 (kappa-B-ras-1) and kappaB-ras-2 are small Ras-like GTPases that associate with Ikappa-B, an inhibitor of the transcription factor NF-kappa-B.
Ikappa-B exists in two homologous forms, Ikappa-B-alpha and Ikappa-B-beta.
Ikappa-B-beta contains a unique 47-amino acid region within its ankyrin domain.
Inactive Ikappa-B-alpha–NF-kappa-B complexes can shuttle between the nucleus and cytoplasm, while Ikappa-B-beta–NF-kappa-B complexes remain cytoplasmic.
KappaB-ras proteins preferentially bind to the Ikappa-B-beta form, modulating its localization and degradation rate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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