Thermo Fisher Scientific SNRPA1 Polyclonal Antibody
Human SNRPA1 단백질을 인식하는 Rabbit Polyclonal 항체. IHC 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. PBS/glycerol buffer에 보관하며, 연구용으로만 사용.
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- PA561757
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SNRPA1. Recombinant protein control fragment (Product # RP-99043) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647696 |
Product Specific Information
Immunogen sequence:
IEQAAQYTNA VRDRELDLRG YKIPVIENLG ATLDQFDAID FSDNEIRKLD GFPLLRRLK
Highest antigen sequence identity:
- Mouse: 100%
- Rat: 100%
Target Information
SNRPA1 (U2 snRNP-A) is located at gene map locus 15q26.3 and encodes a 28 kDa protein.
It is a specific component of the U2 snRNP particle, consisting of a unique N-terminal leucine-rich region and a hydrophobic RNA-binding C-terminal region.
Unlike other RNA-binding proteins, SNRPA1 lacks RNP1 and RNP2 motifs.
It associates with U2 snRNP and participates in transcription and pre-mRNA splicing, potentially playing a role in cell division and proliferation.
Autoantibodies against snRNP particles are often found in patients with connective tissue disorders.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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