Thermo Fisher Scientific GALNT11 Polyclonal Antibody
Human GALNT11 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P)에서 1:500~1:1,000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. PBS 버퍼(40% glycerol) 보존, 4°C 단기/−20°C 장기 보관. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GALNT11. Recombinant protein control fragment (Product # RP-90498) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641840 |
Product Specific Information
Immunogen sequence:
LKTKSYGNIS ERVELRKKLG CKSFKWYLDN VYPEMQISGS HAKPQQPIFV NRGPKRPKVL QRGRLYHLQT NKCLVAQGRP SQKGGLVVLK ACDYSDPNQI WIYNEEHELV LNSLLCLDMS ETRSSDPPRL MKCHGSG
Highest antigen sequence identity to orthologs:
- Mouse: 85%
- Rat: 87%
Target Information
Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).
Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 as GALNT1. Not involved in glycosylation of erythropoietin (EPO).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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