Thermo Fisher Scientific TRAcP (Tartrate-Resistant Acid Phosphatase) Recombinant Mouse Monoclonal Antibody (rACP5, 1070)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1–2 µg/mL

Peptide Array (Array)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity toward phosphoproteins, ATP, and 4-nitrophenyl phosphatase.
It is detected in human alveolar macrophages, osteoclasts, spleen, and liver.
Expression increases in spleen and monocytes of patients with Gaucher’s disease; spleenocytes and circulating leukocytes of patients with hairy cell leukemia; spleen of patients with Hodgkin’s lymphoma; and sera of patients undergoing active bone turnover.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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