Thermo Fisher Scientific CPS1/Carbamoyl-Phosphate Synthetase (Hepatocellular Marker) Monoclonal Antibody (SPM615)
CPS1 단백질을 인식하는 Monoclonal Antibody로, 간세포 표지(marker) 연구용. IHC(P), IHC(PFA), ICC/IF에 사용 가능. Human 및 Dog 시료 반응성. 액상 형태로 4°C 보관, Protein A/G 정제.
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- 1373-MSM1X-Px (2개 옵션)
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카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CPS1/Carbamoyl-Phosphate Synthetase (Hepatocellular Marker) Monoclonal Antibody (SPM615)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM615 |
| Immunogen | Recombinant human CPS1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The mitochondrial enzyme encoded by this gene catalyzes the synthesis of carbamoyl phosphate from ammonia and bicarbonate.
This reaction is the first committed step of the urea cycle, which is crucial for the removal of excess urea from cells.
The encoded protein may also represent a core mitochondrial nucleoid protein.
Three transcript variants encoding different isoforms have been identified, and the shortest isoform may not be localized to the mitochondrion.
Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and venoocclusive disease after bone marrow transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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