Thermo Fisher Scientific CPS1/Carbamoyl-Phosphate Synthetase (Hepatocellular Marker) Monoclonal Antibody (CPS1/8416)
CPS1 단백질을 인식하는 단클론 항체로, 간세포 표지자로 활용 가능. 인간 및 개 시료에서 반응. IHC(P) 및 IHC(PFA) 응용에 적합. 고순도 Protein A/G 정제, 액상 형태로 안정적 보관 가능.
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Thermo Fisher Scientific CPS1/Carbamoyl-Phosphate Synthetase (Hepatocellular Marker) Monoclonal Antibody (CPS1/8416)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
- Publications: [참고 문헌 없음]
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
- Publications: [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CPS1/8416 |
| Immunogen | Recombinant human CPS1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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