Thermo Fisher Scientific Cytokeratin 7/17 Monoclonal Antibody (C-46)
Cytokeratin 7/17 단백질을 인식하는 Mouse monoclonal antibody(C-46)로, 인간 및 소 시료에 반응합니다. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합하며, 단백질 A/G로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Cytokeratin 7/17 Monoclonal Antibody (C-46)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C-46 |
| Immunogen | Cytoskeletal preparation from HeLa cells (human cervical carcinoma cells) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Mouse, Rat, Ferret, or Rabbit.
Target Information
Cytokeratins are a subfamily of intermediate filament proteins characterized by remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately 40 kDa and 68 kDa and isoelectric pH between 4.9 and 7.8.
Human cytokeratins are numbered 1 to 20, and their expression patterns are related to epithelial type and degree of differentiation.
Cytokeratin subtype expression is widely used to distinguish different epithelial malignancies.
Cytokeratin antibodies are valuable tools in differential tumor diagnosis (immunohistochemistry), cytopathology, and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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