Thermo Fisher Scientific Antithrombin Monoclonal Antibody (C3)
인간 Antithrombin 단백질을 인식하는 Mouse monoclonal antibody (Clone C3). Western blot, IHC, ICC/IF에 적합하며, Protein A/G로 정제된 액상 형태. PBS와 50% glycerol에 보관하며 -20°C에서 안정적 유지.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C3 |
| Immunogen | Recombinant Antithrombin protein (amino acids 33–464 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899037 |
Target Information
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. It inhibits thrombin and other activated serine proteases of the coagulation system, regulating the blood coagulation cascade.
The protein includes two functional domains:
- Heparin binding domain at the N-terminus of the mature protein
- Reactive site domain at the C-terminus
The inhibitory activity is enhanced by heparin. Over 120 mutations have been identified in this gene, many of which are associated with antithrombin-III deficiency.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-41554_SERPINC1_P01008-1_House_mouse.svg, MA5-41554_SERPINC1_P01008-1_House_mouse_PDP.jpeg)
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