Thermo Fisher Scientific Aquaporin 4 Monoclonal Antibody (C9)
Aquaporin 4 단백질을 인식하는 Mouse monoclonal antibody (Clone C9). Western blot과 IHC(Paraffin)에서 검증됨. Human 시료에 반응하며, Protein A/G로 정제된 액상 형태. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–30 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C9 |
| Immunogen | Recombinant protein Aquaporin 4 (amino acids 178–317 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899039 |
Target Information
In skeletal muscle, AQP4 (aquaporin 4, also known as mercurial insensitive water channel) localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants, and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9, and one of the two AQP10 transcripts are also permeable to urea and glycerol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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