Thermo Fisher Scientific MAP2K1 Monoclonal Antibody (OTI3H5), TrueMAB
MAP2K1(MEK1) 단백질을 인식하는 마우스 단클론 항체로, WB, IHC, ICC/IF에 적합합니다. HEK293T 세포에서 발현된 인간 MAP2K1 재조합 단백질을 면역원으로 제작되었습니다. 세포 성장 및 분화 연구에 활용되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H5 |
| Immunogen | Full length human recombinant protein of human MAP2K1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase functioning in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. It is activated by various growth factors, cytokines, membrane depolarization, and calcium influx. Mek1 activation occurs through phosphorylation at serine 218 and 222 residues by Raf1. It participates in stress response signaling, apoptosis, and cytokine-induced proliferation. Mutations in the MAP2K1 gene can lead to cardiofaciocutaneous syndrome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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