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Thermo Fisher Scientific 53BP1 Polyclonal Antibody, DyLight 650
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DyLight 650으로 표지된 Thermo Fisher Scientific 53BP1 폴리클로날 항체. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 어플리케이션에 사용 가능. 인간 및 여러 종에 반응하며 DNA 손상 반응 연구에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체.
- 카탈로그번호
- PA522753
- 판매단위
- pk
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마지막 업데이트 2025. 08. 03. 오후 11:37
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Thermo Fisher Scientific PA522753 53BP1 Polyclonal Antibody, DyLight 650 100 ul pk판매 단위 pk ·
재고 확인 필요
715,600원VAT 포함 787,160원
Thermo Fisher Scientific · Thermo Fisher Scientific 53BP1 Polyclonal Antibody, DyLight 650
Thermo Fisher Scientific 53BP1 Polyclonal Antibody, DyLight 650
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-Dependent |
| Immunohistochemistry (Frozen) (IHC-F) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1.5 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Fish, Goat, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Epitope maps to residues 350–400 of human tumor protein p53 binding protein 1 (NP_005648.1) |
| Conjugate | DyLight™ 650 |
| Excitation / Emission Max | 651 / 673 nm |
| Form | Liquid |
| Concentration | 0.71 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 50 mM sodium borate |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152714 |
Product Specific Information
- Human has been tested in WB, IHC-P, and ICC/IF.
- Mouse and goat have been tested only in ICC/IF.
- Suggested positive controls: U205, 293T, MO59K cell lysates, and MEF lysates.
Target Information
53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and acts as a substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to double-strand break sites. It may function in checkpoint signaling during mitosis, enhance TP53-mediated transcriptional activation, and participate in DNA repair by maintaining genomic stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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