Thermo Fisher Scientific GPR116 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total GPR116.

Target Information

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways.
G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and respond to a variety of signaling molecules such as hormones and neurotransmitters.
GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein that contains one SEA domain, one GPS domain, and three Ig-like domains, belonging to the GPR family.
Existing as a disulfide-linked homodimer at the cell surface, GPR116 occurs as multiple alternatively spliced isoforms and is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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