Thermo Fisher Scientific APC4 Polyclonal Antibody
APC4 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot에 적합하며, Affinity chromatography로 정제된 고순도 항체입니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ANAPC4 (Accession Q9UJX5), corresponding to amino acid residues L583–R633 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850359 |
Product Specific Information
Antibody detects endogenous levels of total ANAPC4.
Target Information
The anaphase-promoting complex (APC), also known as the cyclosome, facilitates the metaphase–anaphase transition by ubiquitinating specific substrates such as mitotic cyclins and anaphase inhibitors, which are subsequently degraded by the 26S proteasome. The vertebrate APC consists of eight subunits and is highly conserved from yeast to humans. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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