Thermo Fisher Scientific MCM9 Polyclonal Antibody
MCM9 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin)에서 사용 가능. 인간 및 랫트 반응성. Affinity chromatography로 정제된 액상 항체이며, PBS/glycerol buffer에 보관. DNA 복제 및 복구 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MCM9 (Accession Q9NXL9), corresponding to amino acid residues L1055–Q1105 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850362 |
Product Specific Information
This antibody detects endogenous levels of total MCM9.
Target Information
MCM9 is a component of the MCM8–MCM9 complex, which is involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis.
The MCM8–MCM9 complex likely acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51, required for processing aberrant forks into homologous recombination substrates and orchestrating homologous recombination with resection, fork stabilization, and restart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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