Thermo Fisher Scientific STIM2 Polyclonal Antibody
STIM2 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 인간, 마우스, 랫트에 반응하며, 4°C에서 보관.
- 카탈로그번호
- PA520372
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific STIM2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 2.5 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 20 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide from near the carboxy terminus of human STIM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153417 |
Product Specific Information
- A suggested positive control is A-20 cell lysate.
- PA5-20372 can be used with blocking peptide PEP-0489.
Target Information
In T lymphocytes, Ca²⁺ entry following antigen-receptor binding occurs through store-operated Ca²⁺-release-activated Ca²⁺ (CRAC) channels. These channels consist of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), which acts as a Ca²⁺ sensor and activates the CRAC channels by migrating from endoplasmic reticulum-like sites to the plasma membrane.
STIM2, a related molecule, inhibits STIM1-mediated store-operated Ca²⁺ entry and can form complexes with STIM1, suggesting a coordinated role in controlling Ca²⁺ entry. At least three isoforms of STIM2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.