Thermo Fisher Scientific Human PRTFDC1 Synthetic Peptide
Human PRTFDC1 단백질의 중심부 14개 아미노산 서열로 구성된 합성 펩타이드. PA5-20593 항체의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 PBS(pH 7.2)와 0.1% BSA 포함. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the center of human PRTFDC1.
PEP-0713 can be used as a blocking peptide with polyclonal antibody PA5-20593.
Target Information
Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor. CpG islands in the PRTFDC1 promoter can be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibits cell growth, while knockdown promotes proliferation, suggesting a tumor-suppressor role. At least three isoforms of PRTFDC1 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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