Thermo Fisher Scientific Human ACVR1C Synthetic Peptide
Human ACVR1C 단백질의 N-말단 15개 아미노산 서열을 기반으로 한 합성 펩타이드. 폴리클로날 항체 PA5-20597의 블로킹 펩타이드로 사용 가능. 액상 형태, PBS 버퍼에 0.1% BSA 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP0717
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the amino terminus of human ACVR1C.
PEP-0717 can be used as a blocking peptide with polyclonal antibody PA5-20597.
Target Information
ACVR1C, a serine/threonine protein kinase, is a type I receptor for the TGFB family of signaling molecules. The receptor complex consists of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors, which autophosphorylate, then bind and activate SMAD transcriptional regulators (SMAD2 and SMAD3). These regulators translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
ACVR1C acts as a receptor for activin AB, activin B, and NODAL, playing roles in cell differentiation, growth arrest, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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