Thermo Fisher Scientific HTR2B Polyclonal Antibody
HTR2B 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 인간 및 비인간 영장류 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 4–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from 2nd extracellular domain of human 5HT2B Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550687 |
Product Specific Information
- This antibody is not recommended for use in ICC applications.
- Percent identity with other species by BLAST analysis:
- Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%)
- Bovine, Bat (93%)
Target Information
HTR2B is a G-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding induces conformational changes that trigger signaling via G proteins, modulating downstream effectors. HTR2B plays a role in pain perception, behavioral regulation, and is required for normal proliferation of embryonic cardiac myocytes and heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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