Thermo Fisher Scientific Phospho-Lck (Tyr505) Recombinant Rabbit Monoclonal Antibody (LckY505-A3), PE
인간 Lck 단백질의 Tyr505 인산화 부위를 특이적으로 인식하는 재조합 토끼 단일클론 항체. PE 형광표지로 유세포분석(Flow Cytometry)에 최적화. 높은 특이성과 재현성을 제공하며 연구용으로만 사용 가능.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | LckY505-A3 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr505 of human phospho Lck |
| Conjugate | PE |
| Excitation/Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897275 |
Additional Formats
Target Information
LCK is a member of the Src-family tyrosine kinases essential for T-cell receptor (TCR) signaling. Upon TCR activation, LCK phosphorylates ITAM motifs in the zeta subunits, creating binding sites for SH2 domains of ZAP70, which is subsequently phosphorylated and activated. LCK also contributes to LAT adaptor phosphorylation, forming downstream signaling platforms. It is mainly localized to the plasma membrane, with a fraction at the Golgi apparatus potentially involved in Raf activation under weak stimulation. LCK contains N-terminal myristylation and palmitylation sites, a PTK domain, and SH2/SH3 domains mediating protein-protein interactions. It also regulates apoptosis induced by various stimuli. Diseases associated with LCK include Immunodeficiency 22 and CD45 deficiency. Alternative splice variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-Lck (Tyr505) Recombinant Rabbit Monoclonal Antibody (LckY505-A3), APC
265,000원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-Lck (Tyr505) Recombinant Rabbit Monoclonal Antibody (LckY505-A3), FITC
265,000원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-Lck (Tyr505) Recombinant Rabbit Monoclonal Antibody (LckY505-A3), PE
265,000원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-PDPK1 (Ser241) Recombinant Rabbit Monoclonal Antibody (PDK1S241-F7), APC
265,000원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-PDPK1 (Ser241) Recombinant Rabbit Monoclonal Antibody (PDK1S241-F7), FITC
265,000원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|