Thermo Fisher Scientific Human BCL2A1 Synthetic Peptide
Human BCL2A1 단백질의 N-말단 13개 아미노산 서열에 해당하는 합성 펩타이드로, 항체 차단 실험용으로 사용 가능. 정제된 액상 형태이며 PBS 버퍼에 0.1% BSA 포함. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP0384
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the amino terminus of human Bfl-1.
PEP-0384 can be used as a blocking peptide with polyclonal antibody PA5-20269.
Target Information
Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators involved in various cellular activities such as embryonic development, homeostasis, and tumorigenesis.
The protein encoded by this gene can reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation.
This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators and is up-regulated by extracellular signals such as GM-CSF, CD40, phorbol ester, TNF, and IL-1.
These functions suggest a cytoprotective role essential for lymphocyte activation and cell survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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