Thermo Fisher Scientific HOXB7 Polyclonal Antibody, MaxPab
HOXB7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunocytochemistry에 적합하며, 인간 시료 반응성. Affinity chromatography로 정제된 액상 형태, PBS 버퍼에 보존제 없음. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | HOXB7 (AAH15345.1, 1 a.a. ~ 217 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MSSLYYANAL FSKYPASSSV FATGAFPEQT SCAFASNPQR PGYGAGSGAS FAASMQGLYP GGGGMAGQSA AGVYAAGYGL EPSSFNMHCA PFEQNLSGVC PGDSAKAAGA KEQRDSDLAA ESNFRIYPWM RSSGTDRKRG RQTYTRYQTL ELEKEFHYNR YLTRRRRIEI AHTLCLTERQ IKIWFQNRRM KWKKENKTAG PGTTGQDRAE AEEEEEE
Target Information
The homeobox genes encode transcription factors that regulate developmental processes such as body patterning and organogenesis. The mammalian HOX gene complex consists of 39 genes located on 4 linkage groups (clusters) across 4 chromosomes (HOXA, HOXB, HOXC, and HOXD).
HOXB7 is expressed in most malignant T-cell lines and CD4-positive peripheral blood cells, and is constitutively expressed in melanoma primary lesions and cell lines.
HOXB7 binds to and transactivates bFGF in melanoma cell lines, but SkBr3 breast adenocarcinoma is negative for both HOXB7 and bFGF expression.
HOXB7 may be a key activator of tumor-associated neoangiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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