Thermo Fisher Scientific HOXB8 Monoclonal Antibody (4F8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4F8

Immunogen

HOXB8 (NP_076921, 16 a.a. approximately 114 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HOXB8,uniProtId:P17481-1,ncbiNodeId:9606,antigenRange:16-114,antigenLength:243,antigenImageFileName:H00003218-M01A_HOXB8_P17481-1_House_mouse.svg,antigenImageFileNamePDP:H00003218-M01A_HOXB8_P17481-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Sequence of this protein is as follows: GESLRPNYYD CGFAQDLGGR PTVVYGPSSG GSFQHPSQIQ EFYHGPSSLS TAPYQQNPCA VACHGDPGNF YGYDPLQRQS LFGAQDPDLV QYADCKLAA

Target Information

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.