Thermo Fisher Scientific SPDYA Polyclonal Antibody
Human SPDYA 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:200–1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 세포주기 조절 및 DNA 손상 연구용으로 적합.
- 카탈로그번호
- PA564267
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SPDYA (UniProt ID: Q5MJ70-2, antigen range: 181–247, antigen length: 313) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647827 |
Product Specific Information
Immunogen sequence:
CCEEVMAIAP THYIWQRERS VHHSGAVRNY NRDEVQLPRG PSATPVDCSL CGKKRRYVRL GLSSSSS
Highest antigen sequence identity to orthologs:
- Mouse: 97%
- Rat: 94%
Target Information
Speedy A (SPDYA), also known as SPDY1, Ringo3, or SPY1, is a 313 amino acid nuclear protein belonging to the Speedy/Ringo family.
It is highly expressed in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver, spleen, and placenta.
Speedy A regulates the G1/S phase transition of the cell cycle by binding to and activating Cdc2 p34, Cdk2, and p27.
It also mediates cell survival during DNA damage, playing a key role in proper cell cycle progression.
Multiple isoforms exist due to alternative splicing.
The gene encoding Speedy A maps to human chromosome 2, which contains over 1,400 genes and represents nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-64267_SPDYA_Q5MJ70-2_Rabbit.svg, PA5-64267_SPDYA_Q5MJ70-2_Rabbit_PDP.jpeg)
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