Thermo Fisher Scientific CKI epsilon Polyclonal Antibody
Rabbit polyclonal antibody targeting human CKI epsilon (CSNK1E), validated for Western blot and immunoprecipitation. Recognizes mouse and chicken homologs. Supplied as unconjugated liquid form at 0.2 mg/mL, stored at 4°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 366 and 416 of human casein kinase 1, epsilon |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Chicken
Target Information
CSNK1E (CK1 epsilon) is a serine/threonine kinase involved in vesicular trafficking, DNA damage repair, cell cycle progression, and cytokinesis. It phosphorylates key regulatory proteins controlling cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a conserved kinase domain but differ in variable N- and C-terminal domains. Mammals have seven family members: alpha, beta, gamma1, gamma2, gamma3, delta, and epsilon. CK1ε positively regulates Akt, possibly by inhibiting PP2A, and plays an important role in neurodegenerative diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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