
Thermo Fisher Scientific MARCKS Polyclonal Antibody
MARCKS 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 실험에 적합. Human, Mouse, Rat 시료 반응. Affinity chromatography로 정제된 액상 항체로, PBS/glycerol buffer에 보관. Research Use Only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MARCKS (Accession P29966), corresponding to amino acid residues K137–P187 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853572 |
Product Specific Information
Antibody detects endogenous levels of total MARCKS.
Target Information
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and functions as an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and the plasma membrane, resulting in cytoplasmic localization. The protein is involved in cell motility, phagocytosis, membrane trafficking, and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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