Thermo Fisher Scientific DUSP16 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DUSP16. Recombinant protein control fragment (Product #RP-91557). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DUSP16,uniProtId:Q9BY84-1,ncbiNodeId:9606,antigenRange:332-470,antigenLength:665,antigenImageFileName:PA5-82721_DUSP16_Q9BY84-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82721_DUSP16_Q9BY84-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789877

Product Specific Information

Immunogen sequence: KSETPLSPPC ADSATSEAAG QRPVHPASVP SVPSVQPSLL EDSPLVQALS GLHLSADRLE DSNKLKRSFS LDIKSVSYSA SMAASLHGFS SSEDALEYYK PSTTLDGTNK LCQFSPVQEL SEQTPETSPD KEEASIPKK

Target Information

Dual-specificity phosphatases constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP16 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK proteins ERK, JNK, and p38 with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.