Thermo Fisher Scientific HSPBP1 Polyclonal Antibody
Thermo Fisher Scientific의 HSPBP1 Polyclonal Antibody는 인간 HSPBP1 단백질에 특이적인 토끼 IgG 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공되어 안정적이고 재현성 높은 결과를 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HSPBP1. Recombinant protein control fragment (Product #RP-103930). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642581 |
Product Specific Information
Immunogen sequence:
KLKVKSAFLL QNLLVGHPEH KGTLCSMGMV QQLVALVRTE HSPFHEHVLG ALCSLVTDFP QGVRECREPE LGLEELLRHR CQLLQQHEEY QEELEFCEKL LQT
- Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 100%
Target Information
HspBP1 is an Hsp70-interacting protein first isolated from a human heart cDNA library using the yeast two-hybrid system. The ATPase domain of Hsp70 binds HspBP1 and upon binding, inhibits Hsp70 chaperone activity. HspBP1 promotes nucleotide dissociation from Hsc70 and can alter the conformation of the Hsp70 ATPase domain. It regulates Hsp70 activity that requires ATPase.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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