Thermo Fisher Scientific HSPBP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human HSPBP1. Recombinant protein control fragment (Product #RP-103930). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HSPBP1,uniProtId:Q9NZL4-1,ncbiNodeId:9606,antigenRange:245-347,antigenLength:359,antigenImageFileName:PA5-64461_HSPBP1_Q9NZL4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64461_HSPBP1_Q9NZL4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642581

Product Specific Information

Immunogen sequence: KLKVKSAFLL QNLLVGHPEH KGTLCSMGMV QQLVALVRTE HSPFHEHVLG ALCSLVTDFP QGVRECREPE LGLEELLRHR CQLLQQHEEY QEELEFCEKL LQT

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.

Target Information

HspBP1 is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. The ATPase domain of Hsp70 binds HspBP1 and upon binding, inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 (3) and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.