Thermo Fisher Scientific COX15 Polyclonal Antibody
COX15 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 인간·마우스·랫트 반응성을 가집니다. 고순도 Affinity chromatography 정제, -20°C 보관.
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Thermo Fisher Scientific COX15 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human COX15 (Accession Q7KZN9), corresponding to amino acid residues V271–M321 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852727 |
Product Specific Information
Antibody detects endogenous levels of total COX15.
Target Information
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some nuclear.
COX15 (cytochrome c oxidase assembly protein COX15 homolog) is a 410 amino acid multi-pass mitochondrial membrane protein belonging to the COX15/ctaA family.
Existing as two alternatively spliced isoforms, COX15 is predominantly expressed in tissues with high oxidative phosphorylation rates, including brain, heart, and muscle.
Defects in COX15 are associated with Leigh syndrome and cytochrome c oxidase deficiency (COX deficiency).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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